Intracellular Cytokine Panel
Test Code: 404474P
Tests included in this Panel
Cpt Code:88184 (x1) 88185 (x11)
The assay is intended to aid in the evaluation of patients with suspected problems in lymphocyte regulation. Monitoring changes in cytokine synthesis in response to disease states or immune modulators have become an important tool in understanding basic immunological function and disease pathogenesis. Measuring the intracellular cytokine expression by the lymphocyte subpopulations CD8 and CD4 T lymphocytes, NK, and NKT cells provides a mechanism for evaluating function of these individual cell types. This information will be valuable for following immune-compromised patients or patients with graft-versus-host-disease, solid organ transplants, cancer, AIDS, sepsis, autoimmune diseases, shock and tissue injury, allergy and asthma, chronic urticaria metabolic syndrome and mood disorders.
ProcedureWhole blood is stimulated with PMA and ionomycin. Following stimulation cells are stained with antibodies to identify the cell population and cytokine of interest.
This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.
Assay RangeReportable range is 0.1-100%. Reference ranges were established on a population of healthy adults. They should not be considered diagnositc cutoffs.
Causes For RejectionWhole blood frozen or cold. Specimen will be rejected if greater than 24 hours old. Specimen type other than whole blood collected in sodium heparin tube.
Turnaround Time48 hours following receipt
DisclaimerSpecimens are approved for testing in New York only when indicated in the Specimen Type and Specimen Handling field above.
The CPT codes provided are based on Viracor-IBT's interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor-IBT assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.